GLADEL / Let's Talk About Lupus
Let's Talk About Lupus. Overview of an Innovative, High-Reach, Online Program to Fill the Education Gaps of Latin Americans Living With Lupus
Drenkard C, Fuentes-Silva Y, Parente Costa Seguro L, Torres dos Reis-Neto E, Ibañez S, Elera-Fitzcarrald C, Reategui-Sokolova C, Linhares FA, Bermúdez W, Ferreyra-Garrot L, Acosta C, Caballero-Uribe C, Sato E, Bonfa E, Pons-Estel BA.
Journal of Clinical Rheumatology: February 17, 2021 (Publish Ahead of Print - Issue)
DOI: 10.1097/RHU.0000000000001728
Link: https://journals.lww.com/jclinrheum/Abstract/9000/Let_s_Talk_About_Lupus__Overview_of_an_Innovative,.98388.aspx
GLADEL / GLA-GENLES
Differential treatments base on drug-induced gene expression signatures and longitudinal systemic lupus erythematosus stratification
Toro-Domínguez D, Lopez-Domínguez R, García Moreno A, Villatoro-García JA, Martorell-Marugán J, Goldman D, Petri M, Wojdyla D, Pons-Estel BA, Isenberg D, Morales-Montes de Oca G, Trejo-Zambrano MI, García González B, Rosetti F, Gómez-Martín D, Romero-Díaz J, Carmona-Sáez P, Alarcón-Riquelme ME
Sci Rep. 2019 Oct 29;9(1):15502
DOI: 10.1038/s41598-019-51616-9
Link: https://pubmed.ncbi.nlm.nih.gov/31664045/
Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematosus patients
Lanata CM, Nititham J, Taylor KE, Chung SA, Torgerson DG, Seldin MF, Pons-Estel BA, Tusié-Luna T, Tsao BP, Morand EF, Alarcón-Riquelme ME, Criswell LA
PLoS One. 2018 Jun 28;13(6):e0199003
DOI: 10.1371/journal.pone.0199003
Link: https://pubmed.ncbi.nlm.nih.gov/29953444/
A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus
Patel Z, Lu X, Miller D, Forney CR, Lee J, Lynch A, Schroeder C, Parks L, Magnusen AF, Chen X, Pujato M, Maddox A, Zoller EE, Namjou B, Brunner HI, Henrickson M, Huggins JL, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Pons-Estel BA, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Martin J, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Petri M, Scofield RH, Kimberly RP, Edberg JC, Ramsey-Goldman R, Bang SY, Lee HS, Bae SC, Boackle SA, Cunninghame Graham D, Vyse TJ, Merrill JT, Niewold TB, Ainsworth HC, Silverman ED, Weisman MH, Wallace DJ, Raj P, Guthridge JM, Gaffney PM, Kelly JA, Alarcón-Riquelme ME, Langefeld CD, Wakeland EK, Kaufman KM, Weirauch MT, Harley JB, Kottyan LC
Hum Mol Genet. 2018 Jul 1;27(13):2392-2404
DOI: 10.1093/hmg/ddy140
Link: https://pubmed.ncbi.nlm.nih.gov/29912393/
Transancestral mapping and genetic load in systemic lupus erythematosus
Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ
Nat Commun. 2017 Jul 17;8:16021
DOI: 10.1038/ncomms16021
Link: https://pubmed.ncbi.nlm.nih.gov/28714469/
Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome
Sharma R, Harris VM, Cavett J, Kurien BT, Liu K, Koelsch KA, Fayaaz A, Chaudhari KS, Radfar L, Lewis D, Stone DU, Kaufman CE, Li S, Segal B, Wallace DJ, Weisman MH, Venuturupalli S, Kelly JA, Pons-Estel B, Jonsson R, Lu X, Gottenberg JE, Anaya JM, Cunninghame-Graham DS, Huang AJW, Brennan MT, Hughes P, Alevizos I, Miceli-Richard C, Keystone EC, Bykerk VP, Hirschfield G, Nordmark G, Bucher SM, Eriksson P, Omdal R, Rhodus NL, Rischmueller M, Rohrer M, Wahren-Herlenius M, Witte T, Alarcón-Riquelme M, Mariette X, Lessard CJ, Harley JB, Ng WF, Rasmussen A, Sivils KL, Scofield RH
Arthritis Rheumatol. 2017 Nov;69(11):2187-2192
DOI: 10.1002/art.40207
Link: https://pubmed.ncbi.nlm.nih.gov/28692793/
X chromosome dose and sex bias in autoimmune diseases: Increased 47,XXX in systemic lupus erythematosus and Sjögren's syndrome
Liu K, Kurien BT, Zimmerman SL, Kaufman KM, Taft DH, Kottyan LC, Lazaro S, Weaver CA, Ice JA, Adler AJ, Chodosh J, Radfar L, Rasmussen A, Stone DU, Lewis DM, Li S, Koelsch KA, Igoe A, Talsania M, Kumar J, Maier-Moore JS, Harris VM, Gopalakrishnan R, Jonsson R, Lessard JA, Lu X, Gottenberg JE, Anaya JM, Cunninghame-Graham DS, Huang AJ, Brennan MT, Hughes P, Illei GG, Miceli-Richard C, Keystone EC, Bykerk VP, Hirschfield G, Xie G, Ng WF, Nordmark G, Eriksson P, Omdal R, Rhodus NL, Rischmueller M, Rohrer M, Segal BM, Vyse TJ, Wahren-Herlenius M, Witte T, Pons-Estel BA, Alarcon-Riquelme ME, Guthridge JM, James JA, Lessard CJ, Kelly JA, Thompson SD, Gaffney PM, Montgomery CG, Edberg JC, Kimberly RP, Alarcón GS, Langefeld CL, Gilkeson GS, Kamen DL, Tsao BP, McCune WJ, Salmon JE, Merrill JT, Weisman MH, Wallace DJ, Utset TO, Bottinger EP, Amos CI, Siminovitch KA, Mariette X, Sivils KL, Harley JB, Scofield RH
Arthritis Rheumatol. 2016 May;68(5):1290-1300
DOI: 10.1002/art.39560
Link: https://pubmed.ncbi.nlm.nih.gov/26713507/
Genomic Insights into the ancestry and demographic history of South America
Homburger JR, Moreno-Estrada A, Gignoux CR, Nelson D, Sanchez E, Ortiz-Tello P, Pons-Estel BA, Acevedo-Vasquez E, Miranda P, Langefeld CD, Gravel S, Alarcón-Riquelme ME, Bustamante CD
PLoS Genet. 2015 Dec 4;11(12):e1005602
DOI: 10.1371/journal.pgen.1005602
Link: https://pubmed.ncbi.nlm.nih.gov/26636962/
GWAS in an Amerindian ancestry population reveals novel systemic lupus erythematosus risk loci and the role of European admixture
Alarcón-Riquelme ME, Ziegler JT, Molineros J, Howard TD, Moreno-Estrada A, Sánchez-Rodríguez E, Ainsworth HC, Ortiz-Tello P, Comeau ME, Rasmussen A, Kelly JA, Adler A, Acevedo-Vázquez E, Cucho JM, la Torre IG, Cardiel MH, Miranda P, Catoggio L, Maradiaga-Ceceña M, Gaffney P, Vyse T, Criswell LA, Tsao BP, Sivils KL, Bae SC, James JA, Kimberly R, Kaufman K, Harley JB, Essquivel-Valerio J, Moctezuma JF, García MA, Berbotto G, Babini A, Scherbarth H, Toloza S, Baca V, Nath SK, Salinas CA, Orozco L, Tusié-Luna T, Zidovetzki R, Pons-Estel BA, Langefeld CD, Jacob CO
Arthritis Rheumatol. 2016 Apr;68(4):932-43
DOI: 10.1002/art.39504
Link: https://pubmed.ncbi.nlm.nih.gov/26606652/
Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome Vu?kovi? F, Krišti? J, Gudelj I, Teruel M, Keser T, Pezer M, Pu?i?-Bakovi? M, Štambuk J, Trbojevi?-Akma?i? I, Barrios C, Pavi? T, Menni C, Wang Y, Zhou Y, Cui L, Song H, Zeng Q, Guo X, Pons-Estel BA, McKeigue P, Leslie Patrick A, Gornik O, Spector TD, Harja?ek M, Alarcon-Riquelme M, Molokhia M, Wang W, Lauc G
Arthritis Rheumatol. 2015 Nov;67(11):2978-89
DOI: 10.1002/art.39273
Link: https://pubmed.ncbi.nlm.nih.gov/26200652/
PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6
Oparina NY, Delgado-Vega AM, Martinez-Bueno M, Magro-Checa C, Fernández C, Castro RO, Pons-Estel BA, D'Alfonso S, Sebastiani GD, Witte T, Lauwerys BR, Endreffy E, Kovács L, Escudero A, López-Pedrera C, Vasconcelos C, da Silva BM, Frostegård J, Truedsson L, Martin J, Raya E, Ortego-Centeno N, de Los Angeles Aguirre M, de Ramón Garrido E, Palma MJ, Alarcon-Riquelme ME, Kozyrev SV
Ann Rheum Dis. 2015 Mar;74(3):e14
DOI: 10.1136/annrheumdis-2013-204909
Link: https://pubmed.ncbi.nlm.nih.gov/24534757/
MHC associations with clinical and autoantibody manifestations in European SLE
Morris DL, Fernando MM, Taylor KE, Chung SA, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, Langefeld CD, Noble JA, Rioux JD, Seldin MF; Systemic Lupus Erythematosus Genetics Consortium, Vyse TJ, Criswell LA
Genes Immun. 2014 Apr;15(4):210-7
DOI: 10.1038/gene.2014.6
Link: https://pubmed.ncbi.nlm.nih.gov/24598797/
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations
Kim-Howard X, Sun C, Molineros JE, Maiti AK, Chandru H, Adler A, Wiley GB, Kaufman KM, Kottyan L, Guthridge JM, Rasmussen A, Kelly J, Sánchez E, Raj P, Li QZ, Bang SY, Lee HS, Kim TH, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, Shim SC, Lee SS, Han BG, Olsen NJ, Karp DR, Moser K, Pons-Estel BA, Wakeland EK, James JA, Harley JB, Bae SC, Gaffney PM, Alarcón-Riquelme M; GENLES, Looger LL, Nath SK
Hum Mol Genet. 2014 Mar 15;23(6):1656-68
DOI: 10.1093/hmg/ddt532
Link: https://pubmed.ncbi.nlm.nih.gov/24163247/
Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression
Sakurai D, Zhao J, Deng Y, Kelly JA, Brown EE, Harley JB, Bae SC, Alarc?n-Riquelme ME; BIOLUPUS and GENLES networks, Edberg JC, Kimberly RP, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Kaufman KM, Vyse TJ, Jacob CO, Gaffney PM, Sivils KM, James JA, Kamen DL, Gilkeson GS, Niewold TB, Merrill JT, Scofield RH, Criswell LA, Stevens AM, Boackle SA, Kim JH, Choi J, Pons-Estel BA; Argentine Collaborative Group, Freedman BI, Anaya JM, Martin J, Yu CY, Chang DM, Song YW, Langefeld CD, Chen W, Grossman JM, Cantor RM, Hahn BH, Tsao BP
PLoS Genet 2013; 9(10):e1003870
DOI: 10.1371/journal.pgen.1003870
Link: https://pubmed.ncbi.nlm.nih.gov/24130510/
ABIN1 dysfunction as a genetic basis for lupus nephritis
Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney PM, Stevens AM, Freedman BI, Langefeld CD, Tsao BP, Pons-Estel BA, Jacob CO, Kamen DL, Gilkeson GS, Brown EE, Alarcon GS, Edberg JC, Kimberly RP, Martin J, Merrill JT, Harley JB, Kaufman KM, Reveille JD, Anaya JM, Criswell LA, Vila LM, Petri M, Ramsey-Goldman R, Bae SC, Boackle SA, Vyse TJ, Niewold TB, Cohen P, Powell DW
J Am Soc Nephrol. 2013 Nov;24(11):1743-54
DOI: 10.1681/ASN.2013020148
Link: https://pubmed.ncbi.nlm.nih.gov/23970121/
PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes
Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarcón GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Boackle SA, Freedman BI, Tsao BP, Langefeld CD, Vyse TJ, Jacob CO, Pons-Estel BA; Argentine Collaborative Group, Niewold TB, Moser Sivils KL, Merrill JT, Anaya JM, Gilkeson GS, Gaffney PM, Bae SC, Alarcón-Riquelme ME; BIOLUPUS and GENLES Networks, Harley JB, Criswell LA, James JA, Nath SK
PLoS One. 2013 Aug 7;8(8):e69404
DOI: 10.1371/journal.pone.0069404
Link: https://pubmed.ncbi.nlm.nih.gov/23950893/
Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4
Manku H, Langefeld CD, Guerra SG, Malik TH, Alarcon-Riquelme M, Anaya JM, Bae SC, Boackle SA, Brown EE, Criswell LA, Freedman BI, Gaffney PM, Gregersen PA, Guthridge JM, Han SH, Harley JB, Jacob CO, James JA, Kamen DL, Kaufman KM, Kelly JA, Martin J, Merrill JT, Moser KL, Niewold TB, Park SY, Pons-Estel BA, Sawalha AH, Scofield RH, Shen N, Stevens AM, Sun C, Gilkeson GS, Edberg JC, Kimberly RP, Nath SK, Tsao BP, Vyse TJ
PLoS Genet 2013; 9(7):e1003554
DOI: 10.1371/journal.pgen.1003554
Link: https://pubmed.ncbi.nlm.nih.gov/23874208/
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci
Martin JE, Assassi S, Diaz-Gallo LM, Broen JC, Simeon CP, Castellvi I, Vicente-Rabaneda E, Fonollosa V, Ortego-Centeno N, González-Gay MA, Espinosa G, Carreira P; Spanish Scleroderma Group; SLEGEN consortium; U.S. Scleroderma GWAS group; BIOLUPUS, Camps M, Sabio JM, D'alfonso S, Vonk MC, Voskuyl AE, Schuerwegh AJ, Kreuter A, Witte T, Riemekasten G, Hunzelmann N, Airo P, Beretta L, Scorza R, Lunardi C, Van Laar J, Chee MM, Worthington J, Herrick A, Denton C, Fonseca C, Tan FK, Arnett F, Zhou X, Reveille JD, Gorlova O, Koeleman BP, Radstake TR, Vyse T, Mayes MD, Alarcón-Riquelme ME, Martin J
Hum Mol Genet. 2013 Oct 1;22(19):4021-9
DOI: 10.1093/hmg/ddt248
Link: https://pubmed.ncbi.nlm.nih.gov/23740937/
MicroRNA-3148 modulates allelic expression of Toll-like receptor 7 variant associated with systemic lupus erythematosus
Deng Y, Zhao J, Sakurai D, Kaufman KM, Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield RH, Langefeld CD, Kelly JA, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Vyse TJ, Pons-Estel BA; gentine Collaborative Group, Freedman BI, Gaffney PM, Sivils KM, James JA, Gregersen PK, Anaya JM, Niewold TB, Merrill JT, Criswell LA, Stevens AM, Boackle SA, Cantor RM, Chen W, Grossman JM, Hahn BH, Harley JB, Alarc?n-Riquelme ME; BIOLUPUS and GENLES networks, Brown EE, Tsao BP
PLoS Genet. 2013;9(2):e1003336
DOI: 10.1371/journal.pgen.1003336
Link: https://pubmed.ncbi.nlm.nih.gov/23468661/
Fine mapping of Xq28: both MEXP2 and IRAK1 contributre to risk for systemic lupus erythematosus in multiple ancestral groups
Kaufman KM, Zhao J, Kelly JA, Hughes T, Adler A, Sanchez E, Ojwang JO, Langefeld CD, Ziegler JT, Williams AH, Comeau ME, Marion MC, Glenn SB, Cantor RM, Grossman JM, Hahn BH, Song YW, Yu CY, James JA, Guthridge JM, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Anaya JM, Boackle SA, Stevens AM, Freedman BI, Criswell LA, Pons-Estel BA; on behalf of the Argentine Collaborative Group, Lee JH, Lee JS, Chang DM, Scofield RH, Gilkeson GS, Merrill JT, Niewold TB, Vyse TJ, Bae SC, Alarcón-Riquelme ME; on behalf of the BIOLUPUS network, Jacob CO, Sivils KM, Gaffney PM, Harley JB, Sawalha AH, Tsao BP
Ann Rheum Dis. 2013 Mar;72(3):437-44
DOI: 10.1136/annrheumdis-2012-201851
Link: https://pubmed.ncbi.nlm.nih.gov/22904263/
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans
Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G; International MHC and Autoimmunity Genetics Network, Langefeld CD, Noble JA, Rioux JD, Seldin MF; Systemic Lupus Erythematosus Genetics Consortium, Criswell LA, Vyse TJ
Am J Hum Genet. 2012 Nov 2;91(5):778-93
DOI: 10.1016/j.ajhg.2012.08.026
Link: https://pubmed.ncbi.nlm.nih.gov/23084292/
Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations
Sánchez E, Rasmussen A, Riba L, Acevedo-Vasquez E, Kelly JA, Langefeld CD, Williams AH, Ziegler JT, Comeau ME, Marion MC, García-De La Torre I, Maradiaga-Ceceña MA, Cardiel MH, Esquivel-Valerio JA, Rodriguez-Amado J, Moctezuma JF, Miranda P, Perandones CE, Castel C, Laborde HA, Alba P, Musuruana JL, Goecke IA, Anaya JM, Kaufman KM, Adler A, Glenn SB, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Vilá LM, Criswell LA, Gilkeson GS, Niewold TB, Martín J, Vyse TJ, Boackle SA, Ramsey-Goldman R, Scofield RH, Petri M, Merrill JT, Reveille JD, Tsao BP, Orozco L, Baca V, Moser KL, Gaffney PM, James JA, Harley JB, Tusié-Luna T, Pons-Estel BA, Jacob CO, Alarcón-Riquelme ME
Arthritis Rheum. 2012 Nov;64(11):3687-94
DOI: 10.1002/art.34650
Link: https://pubmed.ncbi.nlm.nih.gov/22886787/
Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus
Adrianto I, Wang S, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME; BIOLUPUS and GENLES Networks, Alarcón GS, Anaya JM, Bae SC, Kim JH, Joo YB, Boackle SA, Brown EE, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá LM, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martín J, Merrill JT, Niewold TB, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Wakeland EK, Moser KL, Montgomery CG, Gaffney PM
Arthritis Rheum. 2012 Nov;64(11):3695-705
DOI: 10.1002/art.34642
Link: https://pubmed.ncbi.nlm.nih.gov/22833143/
Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein
Delgado-Vega AM, Dozmorov MG, Quirós MB, Wu YY, Martínez-García B, Kozyrev SV, Frostegård J, Truedsson L, de Ramón E, González-Escribano MF, Ortego-Centeno N, Pons-Estel BA, D'Alfonso S, Sebastiani GD, Witte T, Lauwerys BR, Endreffy E, Kovács L, Vasconcelos C, da Silva BM, Wren JD, Martin J, Castillejo-López C, Alarcón-Riquelme ME
Ann Rheum Dis. 2012 Jul;71(7):1219-26
DOI: 10.1136/annrheumdis-2011-200987
Link: https://pubmed.ncbi.nlm.nih.gov/22696686/
Association study of IRAK-M and SIGIRR genes with SLE in a large European-descent population
Sánchez E, García-Bermúdez M, Jiménez-Alonso J, de Ramón E, Sánchez-Román J, Ortego-Centeno N, Witte T, D'Alfonso S, Pons-Estel B, Anders HJ, Alarcón-Riquelme ME, Martín J
Lupus. 2012 Oct;21(11):1166-71
DOI: 10.1177/0961203312449494
Link: https://pubmed.ncbi.nlm.nih.gov/22634523/
Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries
Kim K, Brown EE, Choi CB, Alarcón-Riquelme ME; BIOLUPUS, Kelly JA, Glenn SB, Ojwang JO, Adler A, Lee HS, Boackle SA, Criswell LA, Alarcón GS, Edberg JC, Stevens AM, Jacob CO, Gilkeson GS, Kamen DL, Tsao BP, Anaya JM, Guthridge JM, Nath SK, Richardson B, Sawalha AH, Kang YM, Shim SC, Suh CH, Lee SK, Kim CS, Merrill JT, Petri M, Ramsey-Goldman R, Vilá LM, Niewold TB, Martin J, Pons-Estel BA; GENLES, Vyse TJ, Freedman BI, Moser KL, Gaffney PM, Williams A, Comeau M, Reveille JD, James JA, Scofield RH, Langefeld CD, Kaufman KM, Harley JB, Kang C, Kimberly RP, Bae SC
Ann Rheum Dis. 2012 Nov;71(11):1809-14
DOI: 10.1136/annrheumdis-2011-201110
Link: https://pubmed.ncbi.nlm.nih.gov/22523428/
A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus
Wang S, Adrianto I, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME; BIOLUPUS and GENLES Networks, Alarcón GS, Anaya JM, Bae SC, Kim JH, Joo YB, Boackle SA, Brown EE, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá LM, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Wakeland EK, Moser KL, Montgomery CG, Gaffney PM
Genes Immun. 2012 Jul;13(5):380-7
DOI: 10.1038/gene.2012.6
Link: https://pubmed.ncbi.nlm.nih.gov/22476155/
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study
Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, Adler AJ, Li H, Rasmussen A, Williams AH, Ziegler J, Comeau ME, Marion M, Wakeland BE, Liang C, Ramos PS, Grundahl KM, Gallant CJ, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Bae SC, Boackle SA, Brown EE, Chang DM, Cho SK, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Kim JH, Martin J, Merrill JT, Niewold TB, Park SY, Petri MA, Pons-Estel BA, Ramsey-Goldman R, Reveille JD, Scofield RH, Song YW, Stevens AM, Tsao BP, Vila LM, Vyse TJ, Yu CY, Guthridge JM, Kaufman KM, Harley JB, Wakeland EK, Langefeld CD, Gaffney PM, Montgomery CG, Moser KL; BIOLUPUS Network; GENLES Network
Am J Hum Genet. 2012 Apr 6;90(4):648-60
DOI: 10.1016/j.ajhg.2012.02.023
Link: https://pubmed.ncbi.nlm.nih.gov/22464253/
Evaluation of TRAF6 in a large multiancestral lupus cohort
Namjou B, Choi CB, Harley IT, Alarcón-Riquelme ME; BIOLUPUS Network, Kelly JA, Glenn SB, Ojwang JO, Adler A, Kim K, Gallant CJ, Boackle SA, Criswell LA, Kimberly RP, Brown EE, Edberg J, Alarcón GS, Stevens AM, Jacob CO, Gilkeson GS, Kamen DL, Tsao BP, Anaya JM, Kim EM, Park SY, Sung YK, Guthridge JM, Merrill JT, Petri M, Ramsey-Goldman R, Vilá LM, Niewold TB, Martin J, Pons-Estel BA; Genoma en Lupus Network, Vyse TJ, Freedman BI, Moser KL, Gaffney PM, Williams AH, Comeau ME, Reveille JD, Kang C, James JA, Scofield RH, Langefeld CD, Kaufman KM, Harley JB, Bae SC
Arthritis Rheum. 2012 Jun;64(6):1960-9
DOI: 10.1002/art.34361
Link: https://pubmed.ncbi.nlm.nih.gov/22231568/
Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene
Löfgren SE, Frostegård J, Truedsson L, Pons-Estel BA, D'Alfonso S, Witte T, Lauwerys BR, Endreffy E, Kovács L, Vasconcelos C, Martins da Silva B, Kozyrev SV, Alarcón-Riquelme ME
Genes Immun. 2012 Apr;13(3):268-74
DOI: 10.1038/gene.2011.84
Link: https://pubmed.ncbi.nlm.nih.gov/22218224/
Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis
Lin CP, Adrianto I, Lessard CJ, Kelly JA, Kaufman KM, Guthridge JM, Freedman BI, Anaya JM, Alarcón-Riquelme ME; BIOLUPUS and GENLES Networks, Pons-Estel BA, Martin J, Glenn S, Adler A, Bae SC, Park SY, Bang SY, Song YW, Boackle SA, Brown EE, Edberg JC, Alarcón GS, Petri MA, Criswell LA, Ramsey-Goldman R, Reveille JD, Vila LM, Gilkeson GS, Kamen DL, Ziegler J, Jacob CO, Rasmussen A, James JA, Kimberly RP, Merrill JT, Niewold TB, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Moser KL, Harley JB, Gaffney PM, Montgomery CG
Genes Immun. 2012 Apr;13(3):232-8
DOI: 10.1038/gene.2011.82
Link: https://pubmed.ncbi.nlm.nih.gov/22189356/
Novel association of acid phosphatase locus 1*C allele with systemic lupus erythematosus
Teruel M, Martin JE, Ortego-Centeno N, Jiménez-Alonso J, Sánchez-Román J, de Ramón E, Gonzalez-Escribano MF, Pons-Estel BA, D'Alfonso S, Sebastiani GD, Witte T, Bottini N, González-Gay MA, Alarcón-Riquelme ME, Martin J
Hum Immunol 2012 Jan;73(1):107-10. Epub 2011 Oct 21. Erratum in: Hum Immunol. 2012 Sep;73(9):984
DOI: 10.1016/j.humimm.2011.10.012
Link: https://pubmed.ncbi.nlm.nih.gov/22064183/
Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK
Castillejo-López C, Delgado-Vega AM, Wojcik J, Kozyrev SV, Thavathiru E, Wu YY, Sánchez E, Pöllmann D, López-Egido JR, Fineschi S, Domínguez N, Lu R, James JA, Merrill JT, Kelly JA, Kaufman KM, Moser KL, Gilkeson G, Frostegård J, Pons-Estel BA, D'Alfonso S, Witte T, Callejas JL, Harley JB, Gaffney PM, Martin J, Guthridge JM, Alarcón-Riquelme ME
Ann Rheum Dis. 2012 Jan;71(1):136-42
DOI: 10.1136/annrheumdis-2011-200085
Link: https://pubmed.ncbi.nlm.nih.gov/21978998/
Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus
Sreih A, Ezzeddine R, Leng L, LaChance A, Yu G, Mizue Y, Subrahmanyan L, Pons-Estel BA, Abelson AK, Gunnarsson I, Svenungsson E, Cavett J, Glenn S, Zhang L, Montgomery R, Perl A, Salmon J, Alarcón-Riquelme ME, Harley JB, Bucala R.
Arthritis Rheum. 2011 Dec;63(12):3942-51
DOI: 10.1002/art.30624
Link: https://pubmed.ncbi.nlm.nih.gov/22127710/
Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus
Sanchez E, Nadig A, Richardson BC, Freedman BI, Kaufman KM, Kelly JA, Niewold TB, Kamen DL, Gilkeson GS, Ziegler JT, Langefeld CD, Alarcón GS, Edberg JC, Ramsey-Goldman R, Petri M, Brown EE, Kimberly RP, Reveille JD, Vilá LM, Merrill JT, Anaya JM, James JA, Pons-Estel BA, Martin J, Park SY, Bang SY, Bae SC, Moser KL, Vyse TJ, Criswell LA, Gaffney PM, Tsao BP, Jacob CO, Harley JB, Alarcón-Riquelme ME; BIOLUPUS and GENLES, Sawalha AH
Ann Rheum Dis. 2011 Oct;70(10):1752-7
DOI: 10.1136/ard.2011.154104
Link: https://pubmed.ncbi.nlm.nih.gov/21719445/
Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
Zhao J, Wu H, Khosravi M, Cui H, Qian X, Kelly JA, Kaufman KM, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Adler A, Glenn SB, Alarcón-Riquelme ME; BIOLUPUS Network; GENLES Network, Pons-Estel BA, Harley JB, Bae SC, Bang SY, Cho SK, Jacob CO, Vyse TJ, Niewold TB, Gaffney PM, Moser KL, Kimberly RP, Edberg JC, Brown EE, Alarcon GS, Petri MA, Ramsey-Goldman R, Vilá LM, Reveille JD, James JA, Gilkeson GS, Kamen DL, Freedman BI, Anaya JM, Merrill JT, Criswell LA, Scofield RH, Stevens AM, Guthridge JM, Chang DM, Song YW, Park JA, Lee EY, Boackle SA, Grossman JM, Hahn BH, Goodship TH, Cantor RM, Yu CY, Shen N, Tsao BP
PLoS Genet 2011 May;7(5):e1002079
DOI: 10.1371/journal.pgen.1002079
Link: https://pubmed.ncbi.nlm.nih.gov/21637784/
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus
Adrianto I, Wen F, Templeton A, Wiley G, King JB, Lessard CJ, Bates JS, Hu Y, Kelly JA, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME; BIOLUPUS and GENLES Networks, Anaya JM, Bae SC, Bang SY, Boackle SA, Brown EE, Petri MA, Gallant C, Ramsey-Goldman R, Reveille JD, Vila LM, Criswell LA, Edberg JC, Freedman BI, Gregersen PK, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Park SY, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Moser KL, Webb CF, Humphrey MB, Montgomery CG, Gaffney PM
Nat Genet. 2011 Mar;43(3):253-8
DOI: 10.1038/ng.766
Link: https://pubmed.ncbi.nlm.nih.gov/21336280/
Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
Namjou B, Kothari PH, Kelly JA, Glenn SB, Ojwang JO, Adler A, Alarcón-Riquelme ME, Gallant CJ, Boackle SA, Criswell LA, Kimberly RP, Brown E, Edberg J, Stevens AM, Jacob CO, Tsao BP, Gilkeson GS, Kamen DL, Merrill JT, Petri M, Goldman RR, Vila LM, Anaya JM, Niewold TB, Martin J, Pons-Estel BA, Sabio JM, Callejas JL, Vyse TJ, Bae SC, Perrino FW, Freedman BI, Scofield RH, Moser KL, Gaffney PM, James JA, Langefeld CD, Kaufman KM, Harley JB, Atkinson JP
Genes Immun. 2011 Jun;12(4):270-9
DOI: 10.1038/gene.2010.73
Link: https://pubmed.ncbi.nlm.nih.gov/21270825/
Identification of a Systemic Lupus Erythematosus Susceptibility Locus at 11p13 between PDHX and CD44 in a Multiethnic Study
Lessard CJ, Adrianto I, Kelly JA, Kaufman KM, Grundahl KM, Adler A, Williams AH, Gallant CJ; Marta E. Alarcón-Riquelme on behalf of the BIOLUPUS and GENLES Networks, Anaya JM, Bae SC, Boackle SA, Brown EE, Chang DM, Criswell LA, Edberg JC, Freedman BI, Gregersen PK, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Park SY, Petri MA, Pons-Estel BA, Ramsey-Goldman R, Reveille JD, Song YW, Stevens AM, Tsao BP, Vila LM, Vyse TJ, Yu CY, Guthridge JM, Bruner GR, Langefeld CD, Montgomery C, Harley JB, Scofield RH, Gaffney PM, Moser KL
Am J Hum Genet. 2011 Jan 7;88(1):83-91
DOI: 10.1016/j.ajhg.2010.11.014
Link: https://pubmed.ncbi.nlm.nih.gov/21194677/
Genetically determined amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus
Sanchez E, Webb RD, Rasmussen A, Kelly JA, Riba L, Kaufman KM, Garcia-de la Torre I, Moctezuma JF, Maradiaga-Ceceña MA, Cardiel-Rios MH, Acevedo E, Cucho-Venegas M, Garcia MA, Gamron S, Pons-Estel BA, Vasconcelos C, Martin J, Tusié-Luna T, Harley JB, Richardson B, Sawalha AH, Alarcón-Riquelme ME
Arthritis Rheum. 2010 Dec;62(12):3722-9
DOI: 10.1002/art.27753
Link: https://pubmed.ncbi.nlm.nih.gov/20848568/
A 3'UTR variant is associated with impaired expression of CD226 in T and NK T cells and susceptibility to systemic lupus erythematosus
Löfgren SE, Delgado-Vega AM, Gallant CJ, Sánchez E, Frostegård J, Truedsson L, Garrido ED, Sabio JM, González-Escribano MF, Pons-Estel BA, D'Alfonso S, Witte T, Lauwerys BR, Endreffy E, Kovács L, Vasconcelos C, da Silva BM, Martin J, Alarcón-Riquelme ME, Kozyrev SV
Arthritis Rheum. 2010 Nov;62(11):3404-14
DOI: 10.1002/art.27677
Link: https://pubmed.ncbi.nlm.nih.gov/20669283/
Promoter Insertion/Deletion in the IRF5 Gene Is Highly Associated with Susceptibility to Systemic Lupus Erythematosus in Distinct Populations, But Exerts a Modest Effect on Gene Expression in Peripheral Blood Mononuclear Cells
Lofgren S, Yin H, Delgado-Vega AM, Sanchez E, Lewén S, Pons-Estel BA, Witte T, D'Alfonso S, Ortego-Centeno N, Martin J, Alarcón-Riquelme ME, Kozyrev SV
J Rheumatol. 2010 Mar;37(3):574-8
DOI: 10.3899/jrheum.090440
Link: https://pubmed.ncbi.nlm.nih.gov/20080916/
Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus
Sánchez E, Palomino-Morales RJ, Ortego-Centeno N, Jiménez-Alonso J, González-Gay MA, López-Nevot MA, Sánchez-Román J, de Ramón E, González-Escribano MF, Pons-Estel BA, D'Alfonso S, Sebastiani GD; Italian collaborative group, Alarcón-Riquelme ME, Martín J
Hum Mol Genet. 2009 Oct 1;18(19):3739-48
DOI: 10.1093/hmg/ddp301
Link: https://pubmed.ncbi.nlm.nih.gov/19584085/
Genetic associations of LYN with systemic lupus erythematosus
Lu R, Vidal GS, Kelly JA, Delgado-Vega AM, Howard XK, Macwana SR, Dominguez N, Klein W, Burrell C, Harley IT, Kaufman KM, Bruner GR, Moser KL, Gaffney PM, Gilkeson GS, Wakeland EK, Li QZ, Langefeld CD, Marion MC, Divers J, Alarcón GS, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Reveille JD, McGwin G Jr, Vilá LM, Petri MA, Bae SC, Cho SK, Bang SY, Kim I, Choi CB, Martin J, Vyse TJ, Merrill JT, Harley JB, Alarcón-Riquelme ME; BIOLUPUS and GENLES, Pons-Estel BA. Multicenter Collaborations, Nath SK, James JA, Guthridge JM
Genes Immun. 2009 Jul;10(5):397-403
DOI: 10.1038/gene.2009.19
Link: https://pubmed.ncbi.nlm.nih.gov/19369946/
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans
Liu K, Li QZ, Delgado-Vega AM, Abelson AK, Sánchez E, Kelly JA, Li L, Liu Y, Zhou J, Yan M, Ye Q, Liu S, Xie C, Zhou XJ, Chung SA, Pons-Estel BA, Witte T, de Ramón E, Bae SC, Barizzone N, Sebastiani GD, Merrill JT, Gregersen PK, Gilkeson GG, Kimberly RP, Vyse TJ, Kim I, D'Alfonso S, Martin J, Harley JB, Criswell LA; Profile Study Group; Italian Collaborative Group; German Collaborative Group; Spanish Collaborative Group; Argentinian Collaborative Group; SLEGEN Consortium, Wakeland EK, Alarcón-Riquelme ME, Mohan C
J Clin Invest. 2009 Apr;119(4):911-23
DOI: 10.1172/JCI36728
Link: https://pubmed.ncbi.nlm.nih.gov/19307730/
Replication of the TNFSF4 (OX40L) promoter region association with systemic lupus erythematosus
Delgado-Vega AM, Abelson AK, Sánchez E, Witte T, D'Alfonso S, Galeazzi M, Jiménez-Alonso J, Pons-Estel BA, Martin J, Alarcón-Riquelme ME
Genes Immun. 2009 Apr;10(3):248-53
DOI: 10.1038/gene.2008.95
Link: https://pubmed.ncbi.nlm.nih.gov/19092840/
STAT4 Associates with SLE through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sánchez E, Velázquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy P, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N, Abderrahim H, Pons-Estel BA, Gutiérrez C, Suárez A, González-Escribano MF, Martin J, Alarcón-Riquelme ME
Ann Rheum Dis. 2009 Nov;68(11):1746-53
DOI: 10.1136/ard.2008.097642
Link: https://pubmed.ncbi.nlm.nih.gov/19019891/
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus
Orrú V, Tsai SJ, Rueda B, Fiorillo E, Stanford SM, Dasgupta J, Hartiala J, Zhao L, Ortego-Centeno N, D'Alfonso S; The Italian Collaborative Group, Arnett FC, Wu H, Gonzalez-Gay MA, Tsao BP, Pons-Estel BA, Alarcon-Riquelme ME, He Y, Zhang ZY, Allayee H, Chen XS, Martin J, Bottini N
Hum Mol Genet. 2009 Feb 1;18(3):569-79
DOI: 10.1093/hmg/ddn363
Link: https://pubmed.ncbi.nlm.nih.gov/18981062/
Amerindian ancestry in Argentina is associated with increased risk for systemic lupus erythematosus
Seldin MF, Qi L, Scherbarth HR, Tian C, Ransom M, Silva G, Belmont JW, Gamron S, Allievi A, Palatnik SA, Saurit V, Paira S, Graf C, Guillerón C, Catoggio LJ, Prigione C, Berbotto GA, García MA, Perandones CE, Truedsson L, Abderrahim H, Battagliotti CG, Pons-Estel BA, Alarcon-Riquelme ME
Genes Immun. 2008 Jun;9(4):389-93
DOI: 10.1038/gene.2008.25
Link: https://pubmed.ncbi.nlm.nih.gov/18401351/
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus
Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MV, Sanchez E, Gunnarsson I, Svenungsson E, Sturfelt G, Jönsen A, Truedsson L, Pons-Estel BA, Witte T, D'Alfonso S, Barrizzone N, Danieli MG, Gutierrez C, Suarez A, Junker P, Laustrup H, González-Escribano MF, Martin J, Abderrahim H, Alarcón-Riquelme ME
Nat Genet. 2008 Feb;40(2):211-6
DOI: 10.1038/ng.79
Link: https://pubmed.ncbi.nlm.nih.gov/18204447/
Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus
Kozyrev SV, Lewén S, Reddy PM, Pons-Estel BA; Argentine Collaborative Group, Witte T; German Collaborative Group, Junker P, Laustrup H, Gutiérrez C, Suárez A, Francisca González-Escribano M, Martín J; Spanish Collaborative Group, Alarcón-Riquelme ME
Arthritis Rheum. 2007 Apr;56(4):1234-41
DOI: 10.1002/art.22497
Link: https://pubmed.ncbi.nlm.nih.gov/17393452/
Argentine population genetic structure: Large variance in Amerindian contribution
Seldin MF, Tian Chao, Shigeta R, Scherbarth HR, Silva G, Belmont JW, Kittles R, Gamron S, Allievi A, Palatnik SA, Alvarellos A, Paira S, Caprarulo C, Guilleron C, Catoggio LJ, Prigione C, Berbotto G, Garcia MA, Pernadones CE, Pons-Estel BA, Alarcon-Riquelme ME
Am J Phys Anthropol. 2007 Mar;132(3):455-62
DOI: 10.1002/ajpa.20534
Link: https://pubmed.ncbi.nlm.nih.gov/17177183/
No evidence of association between genetic variants of the PDCD1 ligands and SLE
Abelson AK, Johansson CM, Kozyrev SV, Kristjansdottir H, Gunnarsson I, Svenungsson E, Jönsen A, Lima G, Scherbarth HR, Gamron S, Allievi A, Palatnik SA, Alvarellos A, Paira S, Graf C, Guilleron C, Catoggio LJ, Prigione C, Battagliotti CG, Berbotto GA, Garcia MA, Perandones CE, Truedsson L, Steinsson K, Sturfelt G, Pons-Estel BA, Argentinean Collaborative Group, Alarcón-Riquelme ME
Genes Immun. 2007 Jan;8(1):69-74
DOI: 10.1038/sj.gene.6364360
Link: https://pubmed.ncbi.nlm.nih.gov/17136123/
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, Ortmann WA, Koeuth T, Gonzalez Escribano MF; Argentine and Spanish Collaborative Groups; Pons-Estel BA, Petri M, Daly M, Gregersen PK, Martin J, Altshuler D, Behrens TW, Alarcon-Riquelme ME
Nat Genet. 2006 May;38(5):550-5
DOI: 10.1038/ng1782
Link: https://pubmed.ncbi.nlm.nih.gov/16642019/
Chromosome 17p12-q11 harbors susceptibility loci for systemic lupus erythematosus
Johansson CM, Zunec R, García MA, Scherbarth HR, Tate GA, Paira S, Navarro SM, Perandones CE, Gamron S, Alvarellos A, Graf CE, Manni J, Berbotto GA, Palatnik SA, Catoggio LJ, Battagliotti CG, Sebastiani GD, Migliaresi S, Galeazzi M, Pons-Estel BA, Alarcon-Riquelme ME
Hum Genet. 2004 Aug;115(3):230-8
DOI: 10.1007/s00439-004-1145-3
Link: https://pubmed.ncbi.nlm.nih.gov/15232734/
